| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
ORIGINAL RESEARCH |
From the Departments of Obstetrics and Gynecology and Clinical Chemistry, Turku University Central Hospital; the Departments of Physiology and Biostatistics, University of Turku, Turku; and the Department of Pulmonary Medicine, University of Tampere, Tampere, Finland.
Address reprint requests to: Päivi Polo-Kantola, MD Department of Obstetrics and Gynecology Turku University Central Hospital FIN-20520 Turku Finland E-mail: paivi.polo-kantola{at}tyks.fi
Objective: To evaluate the effect of climacteric vasomotor symptoms on sleep quality measured by self-report and polysomnography in postmenopausal women.
Methods: Seventy-one healthy postmenopausal women were recruited, of whom 63 completed the study. Each subject recorded climacteric symptoms and subjective sleep quality for 14 days. Sleep quality was evaluated objectively by all-night polysomnography using the static charge–sensitive bed.
Results: During polysomnography, a high frequency of climacteric vasomotor symptoms was not associated with changes in sleep latency, percentage of sleep stages, number of arousals, sleep efficiency, or total sleep time. However, a high frequency of climacteric vasomotor symptoms (range 0–8.9, r = .60, P < .001), somatic symptoms (range 0–5.0, r = .25–.44, P < .05), and mental symptoms (range 0–5.0, r = .41–.51, P < .001) was related to impaired subjective sleep quality. In stepwise regression analysis, 32% of the impairment in subjective sleep quality was explained by vasomotor symptoms (P < .001), 14% by palpitations (P < .001), and 4% by mood instability (P = .029). High body mass index predicted impaired objective sleep quality, such as prolonged latencies to stage-2 sleep (r = .27, P = .031) and slow-wave sleep (r = .51, P = .003) and decreased oxygen saturations (r = -.54, P < .001). Older women had decreased sleep efficiency (r = -.27, P = .030) and lower oxygen saturations (r = -.36, P = .004). Serum estradiol level had only a minor effect on objective sleep quality.
Conclusion: Impaired subjective sleep quality associated with climacteric vasomotor symptoms did not manifest as abnormalities in polysomnographic sleep recordings. Body mass index and age appeared to have the strongest effect on objective sleep quality.
This article has been cited by other articles:
|
|
 |
|
  N. Kalleinen, P. Polo-Kantola, S.-L. Himanen, P. Alhola, A. Joutsen, A. S Urrila, and O. Polo Sleep and the menopause - do postmenopausal women experience worse sleep than premenopausal women? Menopause Int, September 1, 2008; 14(3): 97 - 104. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. M. Kravitz, I. Janssen, N. Santoro, J. T. Bromberger, M. Schocken, S. A. Everson-Rose, K. Karavolos, and L. H. Powell Relationship of Day-to-day Reproductive Hormone Levels to Sleep in Midlife Women Arch Intern Med, November 14, 2005; 165(20): 2370 - 2376. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. W. Levine, M. E. Dailey, B. Rockhill, D. Tipping, M. J. Naughton, and S. A. Shumaker Validation of the Women's Health Initiative Insomnia Rating Scale in a Multicenter Controlled Clinical Trial Psychosom Med, January 1, 2005; 67(1): 98 - 104. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Saaresranta, P. Polo-Kantola, E. Rauhala, and O. Polo Medroxyprogesterone in postmenopausal females with partial upper airway obstruction during sleep Eur. Respir. J., December 1, 2001; 18(6): 989 - 995. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
