Pelvic organ prolapse in young women

OBJECTIVE: To determine differences in the characteristics and type of genital prolapse in young women compared with older women. METHODS: A retrospective analysis was performed, identifying 647 women who underwent surgical repair of various types of genital prolapse for the years 1979-1991. One hundred ninety-one patients met our inclusion criteria, having well-documented genital prolapse to or beyond the hymen. Patients were stratified into two age groups, those over 35 years and those 35 or younger. The patients were compared regarding "complexity" of prolapse (ie, the total number of deficient sites per patient), grade of prolapse, parity and coexistent medical conditions. RESULTS: During the study period, 27 young women (mean age +/- standard deviation [SD] 30.3 +/- 3.4 years) and 164 older women (mean age +/- SD 60.6 +/- 11.9 years) met our criteria. Young women were more likely than older women to have 1) potential predisposing medical conditions (congenital anomalies or neurologic or connective tissue diseases) (22.2% versus 6.7%, P < .05), 2) lower mean parity (2.8 versus 3.4, P < .05), 3) only one site of prolapse (56% versus 23%, P < .01), and 4) lower grade of prolapse (33% versus 87% grade 3 or higher, P < .001). CONCLUSION: Young patients undergoing surgery for genital prolapse were more likely to have lower parity and single-site and lower-grade prolapse. A higher than expected prevalence of congenital anomalies, as well as rheumatologic and neurologic diseases in the younger women is intriguing, but further study is necessary before these conditions can be implicated in the genesis of genital prolapse.