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Obstetrics & Gynecology 1975;45:365-368
© 1975 by The American College of Obstetricians and Gynecologists
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Treatment of Clear Cell Adenocarcinoma in Young Females

J TAYLOR WHARTON, MD, FACOG, FELIX N. RUTLEDGE, MD, FACOG, H STEPHEN GALLAGER, MD and GILBERT FLETCHER, MD

From the University of Texas System Cancer Center. M. D. Anderson Hospital and Tumor Institute, Houston, Texas

Abstract

Eight cases of clear cell adenocarcinoma treated at The M. D. Anderson Hospital are reviewed. Six such lesions were primarily vaginal carcinomas and 2 involved the cervix. Five patients with early carcinomas were treated entirely with a transvaginal cone or interstitial irradiation and 4 are living and well, 2 to 8 years after completion of therapy. We believe that this experience justifies further treatment of early clear cell carcinomas with conservative radiation. This form of therapy is particularly important since the DES-exposed patients represent an identifiable high-risk group which should augment the chances for early diagnosis.






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Copyright © 1975 by the American College of Obstetricians and Gynecologists.